MYCN Polyclonal Antibody, 20ul Cell Function Analysis see MIM 187700)-related protein with

see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al

Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus

It has the following selective inhibition: adenosine

This gene is intronless and is clustered with CLDN8 on chromosome 21q22

MYCN Polyclonal Antibody, 20ul Cell Function Analysis see MIM 187700)-related protein withThis gene is a member of the MYC family and encodes a protein with a basic helix loop helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.