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Boggs DL, Nguyen JD, Morgenson D, Taffe MA, Ranganathan M

To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

Ferroptosis Ferroptosis, an iron-dependent form of cell death, is primarily triggered by the accumulation of toxic lipids, especially lipid hydroperoxides [77]