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Raf-1(Phospho Ser289) Polyclonal Antibody, 50ul Immunoassays Homeobox genes

SKU: 78119122606

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Raf-1(Phospho Ser289) Polyclonal Antibody, 50ul Immunoassays Homeobox genesThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Homeobox genes

Isoform 1 of subunit IV is encoded by a different gene

This gene is expressed at high levels in primary neutrophils and primary monocytes

TLRs are highly conserved from Drosophila to humans and share structural and functional similarities

Raf-1(Phospho Ser289) Polyclonal Antibody, 50ul Immunoassays Homeobox genesThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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