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Patients have reported decreased interest in alcohol and nicotine when taking GLP-1s, and observational studies have shown an association between treatment with GLP-1 medication and lower risk of alcohol and cannabis use disorders, opioid overdose, and alcohol-related hospitalization

However, side effects can still occur, and every patient responds differently

This study aimed to prospectively compare the relative contributions of fasting duration and last GLP-1 dose timing on gastric ultrasound findings, providing evidence to support individualized, risk-based strategies for minimizing aspiration risk in this growing patient population