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The thinking was that rapid, substantial weight loss might thin the bones and raise the risk of fractures, particularly in people who are already vulnerable, like postmenopausal women. Advertisement Surprising new research on semaglutide and fracture risk New research presented at an Endocrine Society meeting in Chicago found that people with type 2 diabetes who took semaglutide not only experienced more weight loss than those taking other diabetes and weight-loss medications, including Trulicity, Contrave and Qsymia, but they also had a 15 percent lower risk of bone fractures

These percentages translate to meaningful real-world changes

Start your intake Why Weight Returns When You Stop GLP-1 Therapy GLP-1 receptor agonists like semaglutide work by reducing hunger signals, slowing stomach emptying, and improving blood sugar control

Safety data from a phase 3 study show that most side effects occurred during the first one to two dose increases and then decreased significantly