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Its structure is given in Figure \(\sf{\PageIndex{25 \) The coordination geometry is an octahedral antiprism and the complex should be considered as involving a Co center in the midst of a B 16 - "molecular drum" held together by cluster bonds

The Potential Molecular and Cellular Mechanism of Flavonoids for Iron Overload Based on the previous research results, we summarized the underlying mechanisms of flavonoids for treating iron overload according to the following three mechanisms: amelioration of iron status by various proteins and pathways, chelation of iron to reduce iron deposition, and resistance to oxidation to reduce iron overload-induced oxidative damage (Figure 3A)

C., & Sharifi-Rad, J

ROS-induced damage accumulation caused by an attenuated activity of NRF2 during aging may induce NF-B and increase the expression pro-inflammatory mediators, such as interleukin-1-beta (IL-1), IL-6, tumor necrosis factor-alpha (TNF-), intercellular adhesion molecule-1 (ICAM-1), and many others [35]