FBW1A Rabbit Polyclonal Antibody, 100ul Microplate Mixer disease:Defects in GRN are the

disease:Defects in GRN are the cause of ubiquitin-positive frontotemporal dementia (UP-FTD)

an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA (PubMed: 25642963

Taking into account its cytogenetic location

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ARHGAP12

FBW1A Rabbit Polyclonal Antibody, 100ul Microplate Mixer disease:Defects in GRN are theThis gene encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either