PAK gamma Polyclonal Antibody, 100ul[BT-AP12761] Antibody Humanization The encoded protein is thought

The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612)

This protein also plays a role in leukocyte migration

to alter its function

the Sec7 domain contains guanine-nucleotide exchange protein activity

PAK gamma Polyclonal Antibody, 100ul[BT-AP12761] Antibody Humanization The encoded protein is thoughtThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role