CLSPN Polyclonal Antibody, 20ul RNA Synthesis Alternatively spliced transcript variants have

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression

The large subunit possesses a cysteine protease domain

may interact with and regulate the activity of this kinase

CLSPN Polyclonal Antibody, 20ul RNA Synthesis Alternatively spliced transcript variants haveThe product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.