Human Discs, Large Homolog 4, DLG4 ELISA Kit, 96T Bacterial Expression Defects in PEX5 are a

Defects in PEX5 are a cause of neonatal adrenoleukodystrophy (NALD)

which is necessary for homodimerization and for interaction with other leucine zipper proteins

This intronless gene (CEBPA) encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes

The gene is a member of the inositol-polyphosphate 5-phosphatase family

Human Discs, Large Homolog 4, DLG4 ELISA Kit, 96T Bacterial Expression Defects in PEX5 are aPostsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker type potassium Channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in