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Furthermore, in vitro and in vivo studies have demonstrated that the inhibition of glycolytic activity resulting from LDHA knockdown confers antitumor effects in pancreatic ductal adenocarcinoma (PDAC) (Li F

These outcomes underscore obesitys physiological characteristics as a chronic disease, where treatment cessation leads to disease recurrence, and emphasize the necessity of sustained intervention to maintain weight loss

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6 Given the reduced appetite and potential for muscle loss, protein needs are generally higher for individuals on GLP-1 therapy compared to standard recommendations