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10.1002/biof.1293 Biofactors 55 GaabJ.HsterD.PeisenR.EngertV.HeitzV.SchadT.et al

Numerous studies had demonstrated that APX3330 specifically inhibited APE1 REDOX signaling in a variety of tumor models in vitro and in vivo, including pancreatic cancer, leukemia, and malignant peripheral nerve sheath tumors (MPNSTs) [28]