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Name: semaglutide.vs tirzepatide vs. Semaglutide: Which is Best for Weight Loss? Semaglutide vs. Tirzepatide: How Weight-Loss
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As typified by exendin-4 (in clinical use as exenatide), the peptide amino acid sequence can be altered to prevent proteolytic degradation, extending circulatory half-life from minutes to hours, whilst retaining full activity at the receptor (Kolterman et al ., 2003)