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If your current diet is low in fiber, the inulin in Pendulum may be responsible for more of your side effects than the bacteria themselves

However, certain weight loss medications may cause changes in the skin due to fast and substantial shedding of pounds

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If you're new to retatrutide or still figuring out the right starting dose and titration schedule, see our detailed guides: Retatrutide Dosage Chart quick-reference table for starting doses, titration steps, and maximum doses by week Retatrutide Dosing Guide full protocol walkthrough including dose timing, injection sites, and managing side effects The general approach for most people starts at a low dose (0.51 mg per week) and titrates up gradually over several weeks, allowing tolerance to GI side effects to develop