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Egr-1 Monoclonal Antibody, 100ul Cell Dissociation Expression of this gene is

SKU: 52680536472

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Egr-1 Monoclonal Antibody, 100ul Cell Dissociation Expression of this gene isThe protein encoded by this gene belongs to the EGR family of C2H2 type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene.

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Description

Expression of this gene is repressed by phsphorylation

by restricting transmission of foreign DNA such as viruses

and is used as a fluorescent tracer in trasfection and transgenic experiments

This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL)

Egr-1 Monoclonal Antibody, 100ul Cell Dissociation Expression of this gene isThe protein encoded by this gene belongs to the EGR family of C2H2 type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene.

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