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What side effects should I expect from semaglutide after Cushings remission? Gastrointestinal side effects nausea, vomiting, diarrhea, and constipation occur in 3045% of patients during dose titration and may last longer in post-Cushings patients (1012 weeks at therapeutic dose) due to slower gut motility recovery from prior cortisol excess

One of its primary roles is slowing down gastric emptying, which is the speed at which food and medicine move from your stomach into your small intestine