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doi:10.1016/S0140-6736(05)66781-5 65

If we conflate access to drugs with access to quality multidisciplinary care, were going down the wrong path altogether

So patients who advance too quickly to a higher dose typically have more severe side effects and may not be able to tolerate the medication. There is no secret extra dose The idea of a golden dose may be tempting for patients, but safety must come first