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Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing The gene is highly polymorphic

SKU: 16682642948

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Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing The gene is highly polymorphicDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative

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Description

The gene is highly polymorphic in the human population

while the carboxy-terminal region is protease sensitive

In unstimulated cells

This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins

Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing The gene is highly polymorphicDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative

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