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Adrenal hyperfunction or overactive adrenals occur when the adrenal glands produce excessive amounts of hormones, including cortisol

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA (2019) Mitophagy inhibits amyloid- and tau pathology and reverses cognitive deficits in models of Alzheimers disease

(Full Deep-Dive) If Part 1 unpacked the basic physiology behind why protein can make you feel tired, Part 2 dives into the deeper mechanisms hormones, digestion speed, neurotransmitter balance, gut-brain feedback, hydration levels, and even your habits around training and recovery

Human Data: While animal studies (mostly in rats) are overwhelmingly positive, large-scale, peer-reviewed human clinical trials are still limited