GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Multiple 5' alternatively spliced variants

Multiple 5' alternatively spliced variants

resulting from the use of alternate polyadenylation signals

Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus

A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis

GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Multiple 5' alternatively spliced variantsThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.