Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 1314890-29-3

1314890-29-3

6-tert-butyl-3a-carboxyhexahydro-alpha5a

β-secretase 1 inhibitory activity and AMP-activated protein kinase activation of Callyspongia samarensis extracts

Pyridone 6 suppresses osteoclast formation and bone resorption through down-regulation of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand (RANKL)-induced c-Fos and nuclear factor of activated T cells (NFAT) c1 expression

Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 1314890-29-3Regorafenib (Stivarga, BAY 73 4506) Hydrochloride is a multi target inhibitor for VEGFR1, Murine VEGFR2 3, PDGFR, Kit (c Kit), RET (c RET) and Raf 1 with IC50 of 13 nM, 4. 2 nM 46 nM, 22 nM, 7 nM, 1. 5 nM and 2. 5 nM, respectively. Product information CAS Number: 835621 07 3 Molecular Weight: 519. 28 Formula: C21H16Cl2F4N4O3 Synonym: BAY73 4506 hydrochloride Chemical Name: 4 [4 ({[4 chloro 3 (trifluoromethyl)phenyl]carbamoyl}amino) 3 fluorophenoxy] N