TMPS2 Rabbit Polyclonal Antibody, 100ul General Lab Use Mutations in this gene have

Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS)

a chromosomal region involved in both translocations and deletions in human malignancies

each possessing transmembrane regions

This gene encodes a zinc finger containing protein that functions in the regulation of transcription

TMPS2 Rabbit Polyclonal Antibody, 100ul General Lab Use Mutations in this gene haveThis gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain a receptor class A domain a scavenger receptor cysteine rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up regulated by androgenic hormones in prostate cancer cells and down regulated in androgen independent