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While these can be disruptive, they are usually temporary

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Modified morphology (porous powders, shape irregularity) and surface roughness of the carriers, associated with reduced drug-carrier adhesive forces that facilitated drug-carrier detachment can lead to improved lung depositions

Agathisflavone has been found to significantly increase the number of neuronal progenitor cells and mature neurons without increasing astrocytes or microglia, and also to effectively reduce the inflammatory factors factor-, interleukin-6, interleukin-1, NO, and PGE2 (Bakhtiari et al., 2017)