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If CagriSema receives regulatory approval, it would likely become the standard of care for obesity treatment, potentially displacing semaglutide and tirzepatide as first-line options

Research identifies over 4,000 genes influenced by this compound, affecting everything from collagen production to inflammation to wound healing

In animal models, researchers measure parameters such as circulating free fatty acids, respiratory exchange ratios, and adipose tissue gene expression to characterize shifts in substrate utilization

Some are, including GLP-1 receptor agonists (semaglutide, tirzepatide), insulin, and a range of hormone-based therapeutics