glp 1 discontinuation GLP-1 Discontinuation: What It Means for Weight Loss Brands Patients with diabetes who remained

(2025) T2DM: 46.5% discontinued by 1 year 64.1% discontinued by 2 years Without T2DM: 64.8% discontinued by 1 year 84.4% discontinued by 2 years Key Factors Linked to Discontinuation: Higher rates among patients without T2DM Age 65 years More likely to discontinue Higher weight loss during treatment Associated with lower discontinuation rates Moderate to severe GI side effects Higher likelihood of stopping treatment Higher income (T2DM only) Lower discontinuation rates Reinitiation of GLP-1: Source: Rodriguez PJ, Zhang V, Gratzl S, et al

GLP-1 discontinuation The discontinuation rate of GLP-1 medication was 53.6% at 1 year and 72.2% at 2 years

Their potential is only realized if patients can afford and access them, said Ezekiel Emanuel, MD, PhD, vice provost for Global Initiatives, co-director, Healthcare Transformation Institute, University of Pennsylvania and senior author on the paper

Weight regain is visible