Mouse DNA-dependent Protein Kinase Catalytic Subunit, PRKDC ELISA Kit , 96T Molecular Sciences The message for this gene

The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney

It associates with polyribosomes

This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X

The gene encoding this form

Mouse DNA-dependent Protein Kinase Catalytic Subunit, PRKDC ELISA Kit , 96T Molecular Sciences The message for this geneSerine threonine protein kinase that acts as a molecular sensor for DNA damage (By similarity). Involved in DNA non homologous end joining (NHEJ) required for double strand break (DSB) repair and V(D)J recombination (By similarity). Must be bound to DNA to express its catalytic properties (By similarity). Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C) (By similarity).