Bovine Insulin-like Growth Factor Binding Protein 5, IGFBP5 ELISA Kit , 96T Bottle-Top Dispenser Dysregulation of this gene has

Dysregulation of this gene has been associated with the growth and progression of certain cancers

Four different regulatory subunits and three catalytic subunits have been identified in humans

in addition to an F-box| this protein contains multiple WD-40 repeats

The introduction of DAP kinase into highly metastatic carcinoma clones lacking DAP kinase expression was shown to result in the suppression of metastasis

Bovine Insulin-like Growth Factor Binding Protein 5, IGFBP5 ELISA Kit , 96T Bottle-Top Dispenser Dysregulation of this gene hasIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.