PIG-Y Polyclonal Antibody, 100ul Bio-Reaction Tube Mutations in this gene have

Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome

Forms a complex with GDP-bound ARF6 and GULP1

These enzymes also act as RNA chaperones| facilitating the correct folding and assembly of tRNAs (McCleverty et al

It is an important mediator involved in many cytokine-induced immune and inflammatory responses

PIG-Y Polyclonal Antibody, 100ul Bio-Reaction Tube Mutations in this gene haveThe protein encoded by PIGY (phosphatidylinositol glycan anchor biosynthesis class Y)is part of the GPI N acetylglucosaminyltransferase (GIP GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell cell interactions. The transcript for PIGY is bicistronic. The