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Refametinib (R) loxacin Hydrochloride 24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30

SKU: 32841228880

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Refametinib (R) loxacin Hydrochloride 24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1 2 in enzyme inhibition assays. Refametinib R has been reported to inhibit MEK activity and inhibit anchorage dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models. Product information CAS Number: 923032 38 6 Molecular Weight: 572. 34 Formula: C19H20F3IN2O5S Synonym: BAY 869766 R

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24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30

AY 77 exhibits bias for Ca2+ over ERK1/2 signaling (EC50 values are 40 nM for Ca2+ release versus 2 μM for ERK1/2 phosphorylation)

CAS Number: 266359-83-5

CAS Number: 924296-18-4

Refametinib (R) loxacin Hydrochloride 24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1 2 in enzyme inhibition assays. Refametinib R has been reported to inhibit MEK activity and inhibit anchorage dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models. Product information CAS Number: 923032 38 6 Molecular Weight: 572. 34 Formula: C19H20F3IN2O5S Synonym: BAY 869766 R

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