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Luo Y, Gao J, Jiang X, Zhu L, Zhou QT, Murray M, Li J, Zhou F (2023) Molecular insights to the structure-interaction relationships of human proton-coupled oligopeptide transporters (PepTs)

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A more open helical bundle is observed for the TT-OAD2-bound GLP-1R than either GLP-1- or ExP5-bound owing to a distinction in the conformations of TM1, TM6, TM7 and ECL3 at the extracellular side of the receptor induced by the binding of the different ligands (left and middle)