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For example, an athlete returns to training and preparing for competitions after a long break, begins a new and difficult training cycle, or an athlete is exposed to such stresses as being on high ground (for example, in mountains), in a place where smog accumulates, or in very hot or cold climatic conditions

Increasing the dose does not necessarily improve outcomes and may increase the likelihood of unwanted effects

Combining acetaminophen with one NSAID is safe and often more effective than either alone, but never take multiple NSAIDs together (including aspirin) as this multiplies risks without adding benefits