KPYR Polyclonal Antibody, 50ul Cell Screening and Imaging This gene belongs to a

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes

Activation-induced cytidine deaminase is involved in somatic hypermutation

hepatosplenomegaly

|tissue specificity:Expressed in hematopoietic cells and also in colon and testis

KPYR Polyclonal Antibody, 50ul Cell Screening and Imaging This gene belongs to aThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.