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331,332 As a bridge of intercellular communication, classical exosomes have a monolayer structure, which can encapsulate bioactive substances, such as proteins, lipids, DNA, and RNA, in the core and deliver them to effector cells to play specific biological functions (Fig

The most frequently observed adverse reactions with codeine administration include drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, sweating, and constipation