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Heres how to tell them apart: Characteristics of tretinoin purge: Occurs within the first 4-6 weeks of starting tretinoin Breakouts appear in areas where you typically get acne Pimples seem to come and go faster than usual Your skin feels dry or flaky Gradual improvement after 6-8 weeks Signs of an actual breakout: New pimples in unusual places Persistent or worsening acne beyond 6-8 weeks Severe irritation or burning Large cystic breakouts Understanding these differences helps you determine whether youre experiencing a normal tretinoin skin purge or if you need to adjust your routine