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They work synergistically to neutralize free radicals, where vitamin C helps regenerate glutathione, and glutathione helps maintain the efficacy of vitamin C, leading to better overall antioxidant protection

1991): moreover, the positive inotropic effect of isoprenaline was reduced by PIA and carbachol which interfered at various steps in this cascade

Additionally, the trial design may lead to higher screening failure rates in non-White populations and thus trial populations may not be representative