Menin Polyclonal Antibody, 100ul Glassware Impaired spindle checkpoint function has

Impaired spindle checkpoint function has been found in many forms of cancer

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol

The pre-mRNA processing factor 6 encoded by PRPF6 appears to be involved in pre-mRNA splicing

which transcribes DNA into ribosomal RNA precursors

Menin Polyclonal Antibody, 100ul Glassware Impaired spindle checkpoint function hasMEN1 encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative