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PIGQ Polyclonal Antibody, 50ul Cell Dissociation Contains 1 CAP-Gly domain

SKU: 1925363517

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PIGQ Polyclonal Antibody, 50ul Cell Dissociation Contains 1 CAP-Gly domainThis gene is involved in the first step in glycosylphosphatidylinositol (GPI) anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N acetylglucosamine (GlcNAc) from UDP GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding

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Description

Contains 1 CAP-Gly domain

Unlike other proteins of the group| which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes| the protein encoded by this gene is a non-cycling resident protein of the ER| where it functions as a cargo receptor for glycoproteins

It is similar to a rat protein which is a specific partner for the tail domain of myosin V

Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML)

PIGQ Polyclonal Antibody, 50ul Cell Dissociation Contains 1 CAP-Gly domainThis gene is involved in the first step in glycosylphosphatidylinositol (GPI) anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N acetylglucosamine (GlcNAc) from UDP GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding

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