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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays Interalpha trypsin inhibitor (ITI) is

SKU: 6263998258

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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays Interalpha trypsin inhibitor (ITI) isHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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Description

Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain

Also referred to as an acid-sensitive potassium channel

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability

HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04160] Immunoassays Interalpha trypsin inhibitor (ITI) isHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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