RGRF1 Polyclonal Antibody, 100ul Protein Analysis Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include protein homodimerization activity

and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia

is amplified in these cells lines

Some pathogens use this O-linked carbohydrate unit for host entry

RGRF1 Polyclonal Antibody, 100ul Protein Analysis Gene Ontology (GO) annotations relatedThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta gamma subunit. Mouse studies