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A 2025 randomized clinical trial published in JAMA Psychiatry studied once-weekly semaglutide in adults with alcohol use disorder

This approach utilizes a special type of MRI sequence to measure the diffusion of water molecules within myelin, providing a more sensitive way to evaluate the distribution and density of myelin across different brain regions [39]

For hepatic impairment specifically, the evidence hierarchy places the current knowledge base at Level 5 (expert opinion and mechanistic reasoning) on the Oxford Centre for Evidence-Based Medicine scale [11]

Discontinuing after three months resembles stopping an antibiotic after one weekthe infection may temporarily improve, but resistance and relapse frequently occur