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Both RickA and Sca2 contribute to cell-to-cell spread, however Sca2-based motility is the major mediator of cell-to-cell spread 34,35,36,37,64

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Another theory is that the anaerobic bacteria responsible for developing Acne called Propionibacterium acnes feeds on Vit B12

Histidine supplementation has also been linked to improved immune function and stress recovery in several other fish species, highlighting its broader significance in aquaculture for promoting fish health and welfare under challenging environmental conditions [46]