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Persian and Russian healers knew it as mumiyo, "preserver of the body." They applied it for wound healing and tissue regeneration [3]

Only one study [149] showed some concerns in the domains related to the randomization process and deviations from intended interventions, as it lacked a control group and employed a quasi-experimental design (Figure 2)

200 Unlike acute inflammatory responses triggered by infection or injury, this persistent inflammatory phenotype arises from the dynamic interplay of multiple factors, including long-term immune system dysregulation, cellular stress responses, and metabolic derangements