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Actinin-Alpha2/3 Polyclonal Antibody, 50ul Serum & Sample Tubes including fibroblasts and osteoclasts

SKU: 32910072263

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Actinin-Alpha2/3 Polyclonal Antibody, 50ul Serum & Sample Tubes including fibroblasts and osteoclastsAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac,

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including fibroblasts and osteoclasts

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The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions| including cytokinesis| cell motility and maintenance of cell shape

Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome

Actinin-Alpha2/3 Polyclonal Antibody, 50ul Serum & Sample Tubes including fibroblasts and osteoclastsAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac,

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