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In brief, berberine can reduce anti-apoptotic factors (Bax/bcl-2, caspase), autophagy related proteins (IL-3, Beclin, etc.), A pathology, and activate PI3K-AKT and other signaling pathways, and then produce neuroprotective effect (Figure 1)

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Lactose intolerance is a common condition with an estimated global prevalence of 57% to 65%.10 Hydrogen breath testing, which measures exhaled hydrogen gas after consumption of lactose, is a common tool for diagnosing lactose malabsorption given that hydrogen production in the large intestine only occurs if lactose is malabsorbed in the small intestine

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