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Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts Mutations in CIDEC may contribute

SKU: 81569387888

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Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts Mutations in CIDEC may contributeThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Description

Mutations in CIDEC may contribute to insulin resistant diabetes

For A10P15 Adapters

This subunit is present in 4-5 copies per dynactin molecule

initiates survival pathways and cell proliferation

Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts Mutations in CIDEC may contributeThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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