Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases The C-terminal domain is essential

The C-terminal domain is essential for the homodimerization and the interaction with CBL

The PHOX domain is a phosphoinositide binding domain| and the SNX family members are involved in intracellular trafficking

CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules

disease:Defects in NOTCH1 are a cause of aortic valve disease

Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases The C-terminal domain is essentialThe sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Location regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.,PTM: Phosphorylated on Ser 309 and, to a higher extent, on Ser 404 by MARK3. Dephosphorylated on Ser 404 by PPP2CA.