Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing Several alpha defensin genes appear

Several alpha defensin genes appear to be clustered on chromosome 8

As a consequence

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm

Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing Several alpha defensin genes appearThis gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,