Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes Belongs to the IFRD family

Belongs to the IFRD family

The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia

It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies

Specifically binds to an IL-1 response element in the IL-6 gene

Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes Belongs to the IFRD familyParticipates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852). Forms the activation cluster TLR2: TLR1: CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid raft