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Accessed July 5, 2025

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6 Normal tissue sparing by the optimal weekly time dose fractionation schedule To minimize normal tissue apoptosis and the effect of the LDHS and LDA, there exists an optimal daily fractionation window at approximately 1.82.3 Gy/Fr where the shallowest tangent from the origin touches the cell survival curve at approximately 2 Gy (as clearly seen in Figures 9 and 13 [2, 7, 15])