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It also appears to play a role in fat metabolism, though the exact mechanisms are still being elucidated in clinical research

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For semaglutide, 1015% cumulative reduction is typically reached between 9 and 12 months when treatment is consistently followed and combined with diet and exercise

6,7 How Sermorelin Supports Muscle Preservation in GLP-1 Users GLP-1 receptor agonists such as semaglutide can reduce muscle mass by lowering appetite, caloric intake, and indirectly decreasing anabolic signaling through the GHIGF-1 axis